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Operating as a highly potent synthetic amylin analog, this specific sequence works directly alongside calcitonin receptors to monitor synergistic weight management and delayed gastric emptying without altering general metabolic organs

Science 182 , 171173 (1973)

This is related to the higher apparent -log K d values of Zn(II) with the used reducing agent, which are 5.2 for Zn(II)-GSH, 8.32 for Zn(II)-DTT, and 3.2 for Zn(II)-TCEP (Krel et al